Here are some links I found on the ‘Net to Flash video games with somewhat of a scientific bent. I haven’t had chance yet to play these myself so caveat emptor (actually, the games are free).
Infect. Evolve. Repeat. – http://www.arcadexl.com/sources/swf/game_479.swf
This one from the Science Museum in the UK is a bit like “Gizmos and Gadgets”. You have to manoeuvre a ball past obstacle using some principles of physics. As a neat twist you can also create new configurations of obstacles to play yourself or send to friends: